CCRB RECORD No. 0041
The Binding of Isaac
Determination: Explicit — Denial 3
A voice explicitly called ‘the voice of God’ commands a mother to sacrifice her son — the game's entire framing story.
Built on a dark reinterpretation of Genesis's near-sacrifice of Isaac: a devout mother believes God is commanding her to kill her son, with the game leaving open whether that voice was ever really divine.